4-Methoxy-2-nitrobenzoic acid → 2-Amino-4-methoxybenzoic acid
反応式
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([N+:12]([O-])=O)[CH:4]=1>[Pd].CO>[NH2:12][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]参加物
4
実験手順
4-Methoxy-2-nitrobenzoic acid (3 g, 16.4 mmol) was hydrogenated over palladium on carbon (10%, 300 mg) in methanol (80 mL) at room temperature and normal pressure for 18 hours. The reaction mixture was filtered through celite and concentrated to dryness under reduce pressure to give 2.50 g (100%) of the product as a colorless solid.
後処理
- filtrationThe reaction mixture was filtered through celite and
- concentrationconcentrated to dryness
出典と根拠
- ORDレコード
- ord-f8f4666ef20642c2a03ae86bb6637376
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07875715B2
反応ノート
読み込み中…