Sodium borohydride → (2,2,5,5-Tetramethylcyclopentyl)methanol

HRID 256245ノート

反応式

HRID 256245 の反応式
[CH3:1][C:2]1([CH3:11])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[CH:9]=[O:10].[BH4-].[Na+]>C(O)C>[CH3:1][C:2]1([CH3:11])[CH2:6][CH2:5][C:4]([CH3:7])([CH3:8])[CH:3]1[CH2:9][OH:10]

参加物

4

反応物 2

HCID 4311764Sodium borohydrideHCID 9793878Cyclopentanecarboxaldehyde, 2,2,5,5-tetramethyl-

生成物 1

HCID 13629260(2,2,5,5-Tetramethylcyclopentyl)methanol

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2,2,5,5-Tetramethylcyclopentane-1-carboxaldehyde is dissolved in 95% ethanol and sodium borohydride is added. After 24 hours, the reaction is quenched with 1M HCl and extracted with ether. The extract is washed, dried over MgSO4 and evaporated to yield 2,2,5,5-tetramethyl-1-cyclopentylmethanol.

後処理

  1. customthe reaction is quenched with 1M HCl
  2. extractionextracted with ether
  3. washThe extract is washed
  4. dry with materialdried over MgSO4
  5. customevaporated

出典と根拠

ORDレコード
ord-b116a7274c60435fa7d0f6ad586f3ec5
出典データセット
uspto-grants-1987_10
特許番号
US04701552

反応ノート

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