Acetic Acid → HCID 14405001、化合物
反応式
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11].C(O)(=O)C.[N+:16]([O-])([OH:18])=[O:17]>ClCCl>[Cl:1][C:2]1[C:7]([F:8])=[C:6]([N+:16]([O-:18])=[O:17])[C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11]参加物
5
実験手順
20 g of 2,6-dichloro-3,5-difluorophenol are introduced into 70 ml of acetic acid, and 8 g of 98% strength nitric acid are added dropwise. The mixture is subsequently stirred for a further 2 hours at room temperature and taken up in 150 ml of dichloromethane, and the solution is washed twice with water. After removing the dichloromethane by distillation, 18 g of product remain. 94% purity according to GC analysis.
後処理
- additionare added dropwise
- washthe solution is washed twice with water
- customAfter removing the dichloromethane
- distillationby distillation, 18 g of product
出典と根拠
- ORDレコード
- ord-ea06658fa5aa4b67a80ea6d01647b260
- 出典データセット
- uspto-grants-1993_11
- 特許番号
- US05260474
反応ノート
読み込み中…