反応式
C(SCC1[C:19]2[C:14](=[CH:15][CH:16]=[C:17](C3C=CC=CC=3OC)[CH:18]=2)[NH:13]C(C)(C)C=1)C1C=CC=CC=1.Br[CH2:31][C:32]1[C:41]2[C:36](=[CH:37][CH:38]=[C:39]([C:42]3[CH:47]=[CH:46][CH:45]=[CH:44][C:43]=3[O:48][CH3:49])[CH:40]=2)[NH:35][C:34]([CH3:51])([CH3:50])[CH:33]=1.C(=O)([O-])[O-].[K+].[K+].C(S)C1C=CC=CC=1>>[CH3:49][O:48][C:43]1[CH:44]=[CH:45][CH:46]=[CH:47][C:42]=1[C:39]1[CH:40]=[C:41]2[C:36](=[CH:37][CH:38]=1)[NH:35][C:34]([CH3:51])([CH3:50])[CH:33]=[C:32]2[CH2:31][NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1参加物
5
反応物 4
生成物 1
実験手順
4-Benzylsulfanylmethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline 80 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline, 69 mg of potassium carbonate, and 52 μL of benzyl mercaptan reacted to give 12 mg of the title compound as an oil.
出典と根拠
- ORDレコード
- ord-e385195cd3f04f889c2d82fe66f1ebfc
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06858627B2
関連ノート
読み込み中…