Methyl iodide → 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

HRID 257943ノート

反応式

HRID 257943 の反応式
[NH2:1][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][O:5][N:6]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[NH2:1][C:2]1[C:3]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][O:5][N:6]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 14155234-Pyridin-3-yl-1,2,5-oxadiazol-3-amine

生成物 1

HCID 190753223-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of 3-(4-amino-1,2,5-oxadiazol-3-yl)pyridine (870 mg, 5.3 mmol) in acetone (20 ml) was added methyl iodide (990 μl , 16 mmol) and the reaction mixture was stirred overnight at room temperature. The title compound precipitated and was collected by filtration (1.1 g, 69%).

後処理

  1. customThe title compound precipitated
  2. filtrationwas collected by filtration (1.1 g, 69%)

出典と根拠

ORDレコード
ord-e3c36da1faa84b0c80ac9aadfa4d4ba8
出典データセット
uspto-grants-1993_11
特許番号
US05264444

反応ノート

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