Pyridine → S-Methylglutathione

HRID 258234

反応式

HRID 258234 の反応式
[NH2:1][C@@H:2]([CH2:6][CH2:7][C:8]([NH:10][C@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH2:12][SH:13])=[O:9])[C:3]([OH:5])=[O:4].N1C=CC=C[CH:22]=1>>[CH3:22][S:13][CH2:12][C@@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[NH:10][C:8](=[O:9])[CH2:7][CH2:6][C@@H:2]([C:3]([OH:5])=[O:4])[NH2:1]

参加物

3

反応物 2

HCID 1049PyridineHCID 124886Glutathione

生成物 1

HCID 115260S-Methylglutathione

実験手順

When glutathione was complexed with Cr(II), no measurable oxidation of the Cr(II) was observed until the appropriate pyridine derivative was added to the complex mixture. At this time, the 280 nm-340 nm charge transfer peak also appeared. At no time were the 450 nm and 585 nm peaks attributable to Cr--S observed. Replacing glutathione with S-methylglutathione gave identical results.

後処理

  1. additionwas added to the complex mixture
  2. additionAt this time, the 280 nm-340 nm charge transfer peak

出典と根拠

ORDレコード
ord-0f98d2e79fb94967b51a506e029bc6aa
出典データセット
uspto-grants-1993_11
特許番号
US05266560

関連ノート

読み込み中…