Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

HRID 258322

反応式

HRID 258322 の反応式
[F:1][CH:2]([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4].[CH2:11]=[O:12]>>[OH:12][CH2:11][C:2]([F:1])([C:7]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4]

参加物

3

実験手順

The process according to the invention is carried out in three stages: dimethyl α-fluoromalonate is first reacted with formaldehyde to give dimethyl α-hydroxymethyl-α-fluoromalonate, the latter is then hydrolyzed and the hydrolysis product is decarboxylated and dehydrated, and finally, the resuiting α-fluoroacrylic acid is esterified with a substituted phenol.

出典と根拠

ORDレコード
ord-2656d61cbb624db69f1b75b0d589929b
出典データセット
uspto-grants-1993_11
特許番号
US05266668

関連ノート

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