5-Norbornene-2-carboxylic acid → Bicyclo[2.2.1]heptane-2-carboxylic acid

HRID 258434

反応式

HRID 258434 の反応式
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH2:3][CH:2]2[C:8]([OH:10])=[O:9]>[C].[Pd]>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[C:8]([OH:10])=[O:9]

参加物

3

反応物 1

HCID 789495-Norbornene-2-carboxylic acid

生成物 1

HCID 79113Bicyclo[2.2.1]heptane-2-carboxylic acid収率 100.8%

試薬・触媒・溶媒 1

HCID 178418390HCID 178418390、化合物溶媒

実験手順

38.8 g (269 mmol) of crude 5-norbornene-2-carboxylic acid was dissolved in 740 ml of solmix, 1.92 g of 5% palladium-carbon powder was added and the mixture was stirred for 17.5 hours under an atmosphere of hydrogen. The catalyst was filtered off, the solvent was distilled away, and 38.0 g of crude 2-norbornanecarboxylic acid was obtained. Crude yield: 100%.

後処理

  1. additionwas added
  2. filtrationThe catalyst was filtered off
  3. distillationthe solvent was distilled away

出典と根拠

ORDレコード
ord-a007d9d920d5419eb401b6a7ad62a729
出典データセット
uspto-grants-1993_11
特許番号
US05266728

関連ノート

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