Phosphonic acid → N-methylpyrrolidone-5,5-diphosphonic acid
反応式
[CH3:1][NH:2][C:3](=O)[CH2:4][CH2:5][C:6]([OH:8])=O.[OH:10][PH:11]([OH:13])=[O:12].P(Cl)(Cl)Cl>O>[CH3:1][N:2]1[C:3]([P:11]([OH:13])(=[O:10])[OH:12])([P:11]([OH:13])(=[O:10])[OH:12])[CH2:4][CH2:5][C:6]1=[O:8]参加物
5
実験手順
28.5 gm of succinic acid monomethylamide (0.216 mol) were melted with 35.4 gm of H3PO3 (0.432 mol) at 70° C. and then slowly mixed with 37.8 ml of PCl3 (0.432 mol). After an additional 5 hours at 70° C., the product was hydrolyzed with 300 ml of H2O. Filtration with activated carbon at the boiling point yielded a clear solution from which the N-methyl-pyrrolidone-5,5-diphosphonic acid was precipitated with ethanol and acetone. Crude yield 4.2 gm (7% of the theory).
後処理
- filtrationFiltration with activated carbon at the boiling point
出典と根拠
- ORDレコード
- ord-f38e98f76e754c79b4b21016fb03adba
- 出典データセット
- uspto-grants-1977_07
- 特許番号
- US04034086
反応ノート
読み込み中…