Sodium Hydroxide → HCID 23684863、化合物
反応式
[OH-].[Na+:2].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[C:15](=[O:16])[C:14]([C:17]([OH:19])=[O:18])=[C:13]([CH3:20])[N:12]=[CH:11]2)=[CH:6][CH:5]=1>CO>[Cl:3][C:4]1[CH:5]=[CH:6][C:7]([N:10]2[C:15](=[O:16])[C:14]([C:17]([O-:19])=[O:18])=[C:13]([CH3:20])[N:12]=[CH:11]2)=[CH:8][CH:9]=1.[Na+:2]参加物
4
実験手順
To 5 ml of 1.0 N aqueous sodium hydroxide solution (5.0 mmoles) diluted with 50 ml of methanol is added one equivalent of 1-(4-chlorophenyl)-1,6-dihydro-4-methyl-6-oxopyrimidine-5-carboxylic acid prepared as in Example 2. After stirring for a short time the resulting slurry (pH 7-8) is evaporated in vacuo. The solid residue is slurried in ether and isolated by vacuum filtration. Drying gives a quantitative yield of sodium 1-(4-chlorophenyl)-1,6-dihydro-4-methyl-6-oxopyrimidine-5-carboxylate, m.p. >250° C.