Ethyl Acetoacetate → 3-Acetyl-7-methoxycoumarin
反応式
[OH:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[C:12](OCC)(=[O:17])[CH2:13][C:14]([CH3:16])=[O:15]>N1CCCCC1>[C:14]([C:13]1[C:12](=[O:17])[O:1][C:2]2[C:3]([CH:4]=1)=[CH:6][CH:7]=[C:8]([O:10][CH3:11])[CH:9]=2)(=[O:15])[CH3:16]参加物
4
実験手順
A mixture of 15.2 g 2-hydroxy-4-methoxybenzaldehyde and 13.5 g ethyl acetoacetate was warmed on a hot plate until solution was attained. Thirty drops of piperidine were added and the reaction mixture continued to be heated gently. After several minutes the reaction mixture solidified. After cooling, the product was recrystallized from a mixture of alcohol and acetonitrile. Yield 20 g.
後処理
- temperaturewas warmed on a hot plate until solution
- temperatureto be heated gently
- waitAfter several minutes the reaction mixture solidified
- temperatureAfter cooling
- customthe product was recrystallized from a mixture of alcohol and acetonitrile
出典と根拠
- ORDレコード
- ord-0dc7f5bd4b6b41e582a9b7b4128509d7
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147552
反応ノート
読み込み中…