Suprofen → p-(2-Thenoyl)hydratropoyl chloride

HRID 258913

反応式

HRID 258913 の反応式
[C:1]1([C:6]([C:8]2[CH:18]=[CH:17][C:11]([CH:12]([CH3:16])[C:13](O)=[O:14])=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:21])=O>C1C=CC=CC=1>[C:1]1([C:6]([C:8]2[CH:18]=[CH:17][C:11]([CH:12]([CH3:16])[C:13]([Cl:21])=[O:14])=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 5359SuprofenHCID 24386Thionyl Chloride

生成物 1

HCID 11747905p-(2-Thenoyl)hydratropoyl chloride

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A mixture of 5.2 parts of p-(2-thenoyl)hydratropic acid, 4.8 parts of thionyl chloride and 32 parts of anhydrous benzene is stirred and refluxed for 3h. 30. The reaction mixture is evaporated and the residue is evaporated once more from benzene, yielding p-(2-thenoyl)hydratropoyl chloride as a residue.

後処理

  1. temperaturerefluxed for 3h
  2. customThe reaction mixture is evaporated
  3. customthe residue is evaporated once more from benzene

出典と根拠

ORDレコード
ord-6b9439048f53451e9dbe69fab35877a6
出典データセット
uspto-grants-1977_07
特許番号
US04035376

関連ノート

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