Ethanol → 2,5-nonanedione

HRID 258947ノート

反応式

HRID 258947 の反応式
[CH3:1][CH2:2][CH2:3][CH2:4][CH:5]=[O:6].[CH:7]([C:9]([CH3:11])=O)=[CH2:8].C(N(CC)CC)C.C([OH:21])C>>[CH3:1][C:2](=[O:21])[CH2:3][CH2:4][C:5](=[O:6])[CH2:8][CH2:7][CH2:9][CH3:11]

参加物

5

反応物 4

HCID 702EthanolHCID 6570Methyl vinyl ketoneHCID 8063PentanalHCID 8471Triethylamine

生成物 1

HCID 111265032,5-nonanedione

実験手順

Following the procedure described in Example 1, 13.5 g (0.05 mol) of Cat. 1, 43.1 g (0.5 mol) of n-valeraldehyde, 35.1 g (0.5 mol) of methyl vinyl ketone, 500 ml of ethanol and 20.2 g (0.2 mol) of triethylamine are heated for 12 hours under nitrogen at the reflux temperature. For working up, the solvent is distilled, the cooled residue is taken up in chloroform, the chloroform phase is washed with dilute sulphuric acid and subsequently with water, the chloroform is removed and the liquid residue is distilled in a waterpump vacuum. Nonane-2,5-dione is obtained.

後処理

  1. distillationthe solvent is distilled
  2. washthe chloroform phase is washed with dilute sulphuric acid and subsequently with water
  3. customthe chloroform is removed
  4. distillationthe liquid residue is distilled in a waterpump vacuum

出典と根拠

ORDレコード
ord-03063fefccd84353b39346574fd8c449
出典データセット
uspto-grants-1977_07
特許番号
US04035395

反応ノート

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