Chlorine → Maltol

HRID 25906

反応式

HRID 25906 の反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]([OH:8])[CH3:7].Cl[O-:10].[Na+].ClCl>O1CCCC1.O>[CH3:7][C:6]1[O:8][CH:5]=[CH:4][C:3](=[O:10])[C:2]=1[OH:1]

参加物

6

反応物 3

HCID 24526ChlorineHCID 1072431-(2-Furyl)ethanolHCID 23665760Sodium Hypochlorite

生成物 1

HCID 8369Maltol

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

To a solution of 1(2-furyl)-1-ethanol (0.05 mole) in 15 ml of tetrahydrofuran and 15 ml of water at 5° C. is added 21.7 ml of 2.8 M sodium hypochlorite solution. Chlorine (0.05 mole) is added to the reaction flask via a gas inlet tube maintaining the reaction temperature below 5° C. The reaction mixture is then heated to reflux and the tetrahydrofuran removed by distillation. Heating is continued for an additional hour. The reaction mixture is cooled and maltol is isolated by the procedure described in Example 1.

後処理

  1. temperaturemaintaining the reaction temperature below 5° C
  2. temperatureThe reaction mixture is then heated
  3. temperatureto reflux
  4. customthe tetrahydrofuran removed by distillation
  5. temperatureHeating
  6. waitis continued for an additional hour
  7. temperatureThe reaction mixture is cooled

出典と根拠

ORDレコード
ord-09e8b01cef48419b8f8d5e7670f29be6
出典データセット
uspto-grants-1979_04
特許番号
US04147705

関連ノート

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