1-Decanol → Decyl methanesulfonate

HRID 259065ノート

反応式

HRID 259065 の反応式
[CH2:1]([OH:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[S:12](Cl)([CH3:15])(=[O:14])=[O:13]>N1C(C)=CC(C)=CC=1C.CCCCCC>[CH3:15][S:12]([O:11][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])(=[O:14])=[O:13]

参加物

5

反応物 2

HCID 81741-DecanolHCID 31297Methanesulfonyl chloride

生成物 1

HCID 5235508Decyl methanesulfonate

試薬・触媒・溶媒 2

HCID 79532,4,6-Trimethylpyridine溶媒HCID 8058Hexane溶媒

実験手順

To a cooled solution of 158.3 grams of 1-decanol in 1.0 liter of collidine is added dropwise 126 grams of mesyl chloride. The resulting mixture is stirred at room temperature for 1.5 hours and then poured onto ice. The reaction mixture is extracted with ether and the ether extracts are washed with 10% hydrochloric acid. The ether extracts are combined, dried over anhydrous sodium sulfate, and the solvent removed under reduced pressure to leave an oil which solidifies upon cooling. The oil is dissolved in n-hexane and cooled to yield as crystals, decyl methylsulfonate.

後処理

  1. additionpoured onto ice
  2. extractionThe reaction mixture is extracted with ether
  3. washthe ether extracts are washed with 10% hydrochloric acid
  4. dry with materialdried over anhydrous sodium sulfate
  5. customthe solvent removed under reduced pressure
  6. customto leave an oil which
  7. temperatureupon cooling
  8. temperaturecooled

出典と根拠

ORDレコード
ord-ecfa66b8ed5a4dfd8452d31c022d96ea
出典データセット
uspto-grants-1977_07
特許番号
US04036828

反応ノート

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