Sodium Hydroxide → Maltol
反応式
CO[CH:3]1[O:8][CH:7]([CH3:9])[C:6](=[O:10])[CH:5]=[CH:4]1.ClCl.[OH-:13].[Na+]>C(O)(=O)C.O>[CH3:9][C:7]1[O:8][CH:3]=[CH:4][C:5](=[O:13])[C:6]=1[OH:10]参加物
6
実験手順
A solution of 6-methoxy-2-methyl-2H-pyran-3(6H)-one (0.01 mole) in 20 ml of acetic acid was treated with gaseous chlorine (0.01 mole) at room temperature. The reaction mixture was then heated to reflux for about one hour, cooled to room temperature, diluted with 20 ml of water, the pH adjusted with 50% NaOH solution to 7.0 and the reaction mixture extracted with chloroform. The chloroform extract was concentrated to yield maltol which was recrystallized from methanol to give the pure product (56%), mp 159.5°-160.5° C.
後処理
- temperatureThe reaction mixture was then heated
- temperatureto reflux for about one hour
- extractionthe reaction mixture extracted with chloroform
- extractionThe chloroform extract
- concentrationwas concentrated
出典と根拠
- ORDレコード
- ord-7f1252b2941e457884750f3b255f5eb4
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147705
反応ノート
読み込み中…