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Piperidine → 1-(2-Ethylhexyl)-3-cyano-4,6-dimethylpyrid-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | Acetylacetone | HCID 31261 | — |
| 反応物 | 2-cyano-N-(2-ethylhexyl)acetamide | HCID 4590704 | — |
| 生成物 | 1-(2-Ethylhexyl)-3-cyano-4,6-dimethylpyrid-2-one | HCID 20312180 | 60% |
反応手順
A mixture of N-(2-ethylhexyl)cyanoacetamide (201.5 g., 1.0 mole), 2,4-pentanedione (100 g., 1.0 mole), piperidine (10 g.) and 2-B-ethanol 300 ml. is refluxed for 24 hours, cooled to room temperature and the solid precipitate is collected by filtration to give 155 g. (60% yield), mp. 84°-89° C. The solid when recrystallized from petroleum ether/benzene has a mp. 89°-90° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04038065 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-eebb1d1a887c465792464673a9ad563e |
| 出典メモ | uspto-grants-1977_07 |