反应详情

A mixture of N-(2-ethylhexyl)cyanoacetamide (201.5 g., 1.0 mole), 2,4-pentanedione (100 g., 1.0 mole), piperidine (10 g.) and 2-B-ethanol 300 ml. is refluxed for 24 hours, cooled to room temperature and the solid precipitate is collected by filtration to give 155 g. (60% yield), mp. 84°-89° C. The solid when recrystallized from petroleum ether/benzene has a mp. 89°-90° C.

1. temperatureis refluxed for 24 hours
2. filtrationthe solid precipitate is collected by filtration
3. customto give 155 g
4. customThe solid when recrystallized from petroleum ether/benzene