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Pyridine → N-(3-(Oxazolo[4,5-b]pyridin-2-yl)phenyl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 3-(Oxazolo[4,5-b]pyridin-2-yl)aniline | HCID 611086 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | N-(3-(Oxazolo[4,5-b]pyridin-2-yl)phenyl)acetamide | HCID 2995970 | — |
反応手順
A solution of 0.63 g. of 2-(3-aminophenyl)oxazolo[4,5-b]pyridine in 10 ml. of pyridine was treated with 0.35 ml. of acetic anhydride with stirring. After stirring over the weekend the mixture was diluted to 50 ml. with water. After stirring a short time and cooling, the precipitate was collected, washed with water and dried. Recrystallization from ethyl acetate gave 2-(3-acetamidophenyl)oxazolo[4,5-b]pyridine, m.p. 201.5°-202.5°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04038396 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-9562b43195984e0c811e2b8a33049552 |
| 出典メモ | uspto-grants-1977_07 |