3-Methoxy-2-methyl-6-nitropyridine → 5-Methoxy-6-methylpyridin-2-amine
反応式
[CH3:1][O:2][C:3]1[C:4]([CH3:12])=[N:5][C:6]([N+:9]([O-])=O)=[CH:7][CH:8]=1>[Pd].CO>[NH2:9][C:6]1[N:5]=[C:4]([CH3:12])[C:3]([O:2][CH3:1])=[CH:8][CH:7]=1参加物
4
実験手順
3-Methoxy-2-methyl-6-nitropyridine (0.317 g.) in 20 ml. of methanol, was hydrogenated over 0.1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 6-amino-3-methoxy-2-methylpyridine, which was used directly in the next step.
後処理
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated to dryness
出典と根拠
- ORDレコード
- ord-995f9faace49482ba693e948bd6d9e76
- 出典データセット
- uspto-grants-1977_07
- 特許番号
- US04038396
反応ノート
読み込み中…