Acetyl chloride → 1-(Azocan-1-yl)ethan-1-one
反応式
[CH2:1]([N:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].C(Cl)(=[O:10])C.O1C[CH2:15][CH2:14][CH2:13]1>>[C:1]([N:3]1[CH2:6][CH2:7][CH2:15][CH2:14][CH2:13][CH2:5][CH2:4]1)(=[O:10])[CH3:2]参加物
4
実験手順
To a stirred solution of heptamethyleneimine (5.56 ml; 44 mmol) and triethylamine (6.13 ml; 44 mmol) in tetrahydrofuran (20 ml) under nitrogen at 0° C. was added dropwise a solution of acetyl chloride (3.13 ml; 44 retool) in tetrahydrofuran (20 ml). The reaction mixture was then warmed to room temperature and stirred for 1 hr. The resulting solid was filtered off and washed thoroughly with ether. The filtrate was evaporated in vacuo to give an orange oil. Distillation in vacuo gave the title compound (D9).
後処理
- filtrationThe resulting solid was filtered off
- washwashed thoroughly with ether
- customThe filtrate was evaporated in vacuo
- customto give an orange oil
- distillationDistillation in vacuo
出典と根拠
- ORDレコード
- ord-81e31281b4be49f29f927bbb73481f98
- 出典データセット
- uspto-grants-1996_06
- 特許番号
- US05523299
反応ノート
読み込み中…