Sodium Hydroxide → N,N-Dibenzyl-L-phenylalanine

HRID 259827ノート

反応式

HRID 259827 の反応式
Cl.[CH2:2]([N:9]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>C(Cl)Cl>[CH2:21]([N:9]([CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 69745698HCID 69745698、化合物

生成物 1

HCID 10980880N,N-Dibenzyl-L-phenylalanine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

N,N-Dibenzyl-L-phenylalanine hydrochloride (50 g) was dissolved in methylene chloride (500 ml), and an aqueous solution of sodium hydroxide (sodium hydroxide 6 g, water 500 ml) was added thereto. After stirring the mixture for 30 minutes, it was partitioned, and the organic layer was dried over magnesium sulfate and concentrated under reduced pressure to give N,N-dibenzyl-L-phenylalanine as an oily substance.

後処理

  1. customit was partitioned
  2. dry with materialthe organic layer was dried over magnesium sulfate
  3. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-5bd915c8abba4ef192747210afc6e22e
出典データセット
uspto-grants-1996_06
特許番号
US05523410

反応ノート

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