Tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate → Tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate

HRID 259919

反応式

HRID 259919 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]([S:12]([O-:15])(=[O:14])=[O:13])[CH3:11])[CH:7]=[CH:8][CH:9]=1)([O-])=O.[CH2:16]([N+:20]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:17][CH2:18][CH3:19]>[Pd].C(O)C>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]([S:12]([O-:15])(=[O:13])=[O:14])[CH3:11])[CH:7]=[CH:8][CH:9]=1.[CH2:29]([N+:20]([CH2:16][CH2:17][CH2:18][CH3:19])([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:25][CH2:26][CH2:27][CH3:28])[CH2:30][CH2:31][CH3:32]

参加物

4

反応物 1

HCID 22917835Tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate

生成物 1

HCID 9803422Tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

反応条件

温度
25 °C

実験手順

0.2 g of 5% strength palladium on charcoal is added to a solution of 2.8 g of the laevorotatory isomer of tetra-n-butylammonium 1-(3-nitrophenyl)ethanesulphonate in 50 cm3 of ethanol. The suspension is stirred for 2 hours at a temperature of about 25° C. under a hydrogen atmosphere (100 kPa). The catalyst is filtered off and the filtrate is concentrated to dryness under reduced pressure (2.7 kPa) at 40° C. 2.8 g of the laevorotatory isomer of tetra-n-butylammonium 1-(3-aminophenyl)ethanesulphonate are thus obtained in the form of an oil, used as such in the subsequent syntheses.

後処理

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated to dryness under reduced pressure (2.7 kPa) at 40° C

出典と根拠

ORDレコード
ord-e4772676ca694072bc9fb6329cecc7d7
出典データセット
uspto-grants-1996_06
特許番号
US05523469

関連ノート

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