Sodium Hydroxide → HCID 10242690、化合物
反応式
Cl.[CH2:2]1[O:10][C:9]2[CH:8]=[CH:7][C:6]([CH:11]([OH:17])[CH2:12][NH:13][CH:14]([CH3:16])[CH3:15])=[CH:5][C:4]=2[O:3]1.[OH-].[Na+]>O>[CH2:2]1[O:10][C:9]2[CH:8]=[CH:7][C:6]([CH:11]([OH:17])[CH2:12][NH:13][CH:14]([CH3:15])[CH3:16])=[CH:5][C:4]=2[O:3]1参加物
4
実験手順
5 g. of 1-(3,4-methylenedioxyphenyl)-2-isopropylaminoethanol hydrochloride are dissolved in 20 mol. of water, and the resulting aqueous solution is made basic with 1N caustic soda. The liberated oil is extracted with ether. The ether layer is separated and dried and the ether is removed by distillation. Upon recrystallization of the crystalline residue from petroleum ether, 1-(3,4-methylenedioxyphenyl)-2-isopropylaminoethanol is obtained as white needle crystals having a melting point of 117°-118° C.
後処理
- extractionThe liberated oil is extracted with ether
- customThe ether layer is separated
- customdried
- customthe ether is removed by distillation
- customUpon recrystallization of the crystalline residue from petroleum ether
出典と根拠
- ORDレコード
- ord-a7be1f2431724a97bf5efa5c8c526b27
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147799
反応ノート
読み込み中…