化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylthiocarbamoyl chloride → Dimethylthiocarbamoyl valine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylthiocarbamoyl chloride | HCID 27871 | — |
| 反応物 | l-Valine, ethyl ester | HCID 87182 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | Dimethylthiocarbamoyl valine | HCID 53885838 | — |
反応手順
Valine ethyl ester (0.0028 mol) in 10 ml acetonitrile was reacted with dimethylthiocarbamoyl chloride (0.0056 mol) at 50° C. for 2 hours. Solvent acetonitrile was removed by rotary evaporation. Trifluoroacetic acid (10 ml) was added and the mixture stirred at room temperature for 15 min. The trifluoroacetic acid was removed by rotary evaporation. The residue was dissolved in water and analyzed by FAB/MS. The expected product, dimethylthiocarbamoyl valine (MH+=205), was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05525707 |
| 出典データセット | uspto-grants-1996_06 |
| ORD ID | ord-7c3f4ac9582a492d88c902c8d1fa939d |
| 出典メモ | uspto-grants-1996_06 |