Benzoyl chloride → HCID 19967563、化合物
反応式
[NH2:1][C:2]1[C:11]2[C:6](=[N:7][C:8]([CH3:12])=[CH:9][N:10]=2)[NH:5][C:4](=[O:13])[N:3]=1.[C:14](Cl)(=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>N1C=CC=CC=1>[C:14]([NH:1][C:2]1[C:11]2[C:6](=[N:7][C:8]([CH3:12])=[CH:9][N:10]=2)[NH:5][C:4](=[O:13])[N:3]=1)(=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1参加物
4
反応条件
- 温度
- 80 °C
実験手順
In 20 mL of pyridine is dissolved 1.63 g (0.01 mole) of 4-amino-7-methyl-pteridine-2-one (20). Then 3.12 g (0.02 mole) of benzoyl chloride is added dropwise while stirring the mixture. The mixture is heated to 80° C. for 30 minutes and then poured on ice. The resulting precipitate is collected, washed with ethanol and ether and then recrystallized from DMF to give 21.