Phosphorus oxychloride → 2-(2,6-Diethyl-3-methylanilino)-2-imidazoline

HRID 260383

反応式

HRID 260383 の反応式
[CH2:1]([C:3]1[C:9]([CH3:10])=[CH:8][CH:7]=[C:6]([CH2:11][CH3:12])[C:4]=1[NH2:5])[CH3:2].C([N:16]1[CH2:20][CH2:19][NH:18][C:17]1=O)(=O)C.O=P(Cl)(Cl)Cl>>[CH2:1]([C:3]1[C:9]([CH3:10])=[CH:8][CH:7]=[C:6]([CH2:11][CH3:12])[C:4]=1[NH:5][C:17]1[NH:18][CH2:19][CH2:20][N:16]=1)[CH3:2]

参加物

4

反応物 3

HCID 24813Phosphorus oxychlorideHCID 79350N-AcetylimidazolidinoneHCID 144235m-Toluidine, 2,6-diethyl-

生成物 1

HCID 224015932-(2,6-Diethyl-3-methylanilino)-2-imidazoline

実験手順

2,6-Diethyl-3-methyl aniline is reacted with N-acetyl-2-imidazolidinone in the presence of POCl3 to produce the imidazoline. This intermediate is treated with sodium hydroxide and water to remove the acetyl group and yield the name compound (VI).

出典と根拠

ORDレコード
ord-269305ddd5f9418ea022ac43d34bd89e
出典データセット
uspto-grants-1996_06
特許番号
US05527830

関連ノート

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