Hydrochloric Acid → HCID 70608900、化合物

HRID 26046

反応式

HRID 26046 の反応式
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH:3]=[CH:2]1.[K].[NH:9]([C:16]1[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.Cl>CC(C)([O-])C.[K+].O.C(O)(C)(C)C>[C:4]([O:22][C:19]1[CH:18]=[CH:17][C:16]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:21][CH:20]=1)(=[O:5])/[CH:3]=[CH:2]\[C:1]([OH:6])=[O:7]

参加物

8

反応物 4

HCID 313Hydrochloric AcidHCID 7923Maleic AnhydrideHCID 312084-Hydroxydiphenylamine2 回HCID 5462222Potassium2 回

生成物 1

HCID 70608900HCID 70608900、化合物

試薬・触媒・溶媒 3

HCID 962Water溶媒HCID 6386tert-Butanol溶媒HCID 23665647Potassium tert-butoxide溶媒

実験手順

4-Anilinophenyl hydrogen maleate was prepared by adding 10 grams of maleic anhydride to a solution of the potassium salt of 4-anilinophenol which was prepared by dissolving 18.5 grams of 4-anilinophenol in a solution of potassium tert.butoxide prepared by reacting 3.9 grams of potassium with 75 milliliters of tert.butyl alcohol. The reaction mixture was stirred for two hours at 65°-70° C. and was then poured into a solution of 12 milliliters of concentrated hydrochloric acid in 138 milliliters of water. The organic layer was separated by extraction with benzene. The extract was washed twice with water and then allowed to evaporate. The residue was recrystallized twice from benzene yielding 1.3 grams of product which melted at 139°-142° C.

後処理

  1. customwas prepared
  2. customprepared
  3. customThe organic layer was separated by extraction with benzene
  4. washThe extract was washed twice with water
  5. customto evaporate
  6. customThe residue was recrystallized twice from benzene yielding 1.3 grams of product which melted at 139°-142° C.

出典と根拠

ORDレコード
ord-39344a9a84f247b1a5f14467327c0645
出典データセット
uspto-grants-1979_04
特許番号
US04147880

関連ノート

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