化工社化工社 化学情報印刷レポート · 研究参考用
2-Methoxyisonicotinonitrile → (2-Methoxypyridin-4-yl)methanamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methoxyisonicotinonitrile | HCID 7204887 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (2-Methoxypyridin-4-yl)methanamine | HCID 16227983 | — |
反応手順
A solution of 4-cyano-2-methoxypyridine (0.55 g, 4.1 mmol) in ethanol was hydrogenated at 60 psi H2 in the presence of 10% Pd/C (100 mg). After 3.5 h the catalyst was removed by filtration through Super-Gel and the liltrate evaporated to give the title compound as a foam.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05527819 |
| 出典データセット | uspto-grants-1996_06 |
| ORD ID | ord-3fa0020c6e9c4e56a9b2fcba963c000d |
| 出典メモ | uspto-grants-1996_06 |