Phenol → 14H-benz[4,5]isoquino[2,1-a]perimidin-14-one

HRID 260890

反応式

HRID 260890 の反応式
C1(O)C=CC=CC=1.[NH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[NH2:19])[CH:12]=[CH:11][CH:10]=1.[CH:20]1[CH:25]=[C:24]2[C:26](O[C:29]([C:31]3=[CH:32][CH:33]=[CH:34][C:22](=[C:23]23)[CH:21]=1)=O)=[O:27]>CO>[CH:16]1[C:17]2=[C:18]3[C:13]([CH:12]=[CH:11][CH:10]=[C:9]3[N:8]=[C:29]3[C:31]4[CH:32]=[CH:33][CH:34]=[C:22]5[CH:21]=[CH:20][CH:25]=[C:24]([C:23]=45)[C:26](=[O:27])[N:19]32)=[CH:14][CH:15]=1

参加物

5

反応物 3

HCID 996PhenolHCID 6693Naphthalic anhydrideHCID 680671,8-Diaminonaphthalene

生成物 1

HCID 8127114H-benz[4,5]isoquino[2,1-a]perimidin-14-one

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

反応条件

温度
150 °C

実験手順

250 g of phenol are melted at about 60° C. 47.4 g of 1,8-diaminonaphthalene and 59.4 g of 1,8-naphthalic acid anhydride are introduced, while passing over nitrogen, and the mixture is heated to 150° C. in the course of 1 hour and kept at this temperature for 2 hours. The reaction mixture is cooled to 80° C., 120 ml of methanol are added at a temperature of 80° to 65° C. in the course of 30 minutes, and the mixture is cooled to room temperature and filtered with suction. After the residue has been washed with 240 ml of methanol and dried at 150° C., 88.8 g of the stated dyestuff are obtained in a very good quality.

後処理

  1. temperatureThe reaction mixture is cooled to 80° C.
  2. temperaturethe mixture is cooled to room temperature
  3. filtrationfiltered with suction
  4. washAfter the residue has been washed with 240 ml of methanol
  5. customdried at 150° C.
  6. custom88.8 g of the stated dyestuff are obtained in a very good quality

出典と根拠

ORDレコード
ord-222415fb05e64196981cfd7fb30e071f
出典データセット
uspto-grants-1996_06
特許番号
US05530130

関連ノート

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