3-Methoxybenzaldehyde → 3-methoxy-beta-methylstyrene Oxide
反応式
[C:1]1([SH+]C2C=CC=CC=2)C=CC=C[CH:2]=1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]=[O:20]>O1CCCC1>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]1[O:20][CH:1]1[CH3:2]参加物
4
反応条件
- 温度
- -78 °C
実験手順
To a -78° C. solution of diphenylsulfonium ethylide (1.0 mole) in tetrahydrofuran (one liter) is slowly added 3-methoxybenzaldehyde (1.0 mole). The reaction mixture is stirred at -78° C. for 3 hours and then allowed to warm to room temperature. It is then added to ether-water and the ether phase separated. The ether phase is washed with water, dried (MgSO4) and evaporated. Fractional distillation of the residue gives the title product.
後処理
- customTo a -78° C.
- temperatureto warm to room temperature
- customthe ether phase separated
- washThe ether phase is washed with water
- dry with materialdried (MgSO4)
- customevaporated
- distillationFractional distillation of the residue
出典と根拠
- ORDレコード
- ord-0870f23e94594ab8af2b681cf027407d
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147872
反応ノート
読み込み中…