反応式
C(OC[N:10]1[CH:14]=[CH:13][N:12]=[C:11]1[C:15]([C:23]1[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=1)([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[OH:16])C1C=CC=CC=1.C(O)(=O)C.Cl>O>[Cl:29][C:26]1[CH:25]=[CH:24][C:23]([C:15]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)([C:11]2[NH:12][CH:13]=[CH:14][N:10]=2)[OH:16])=[CH:28][CH:27]=1参加物
5
実験手順
About 17 g. (0.042 mol) of 1-[(benzyloxy)methyl]-α-(p-chlorophenyl)-α-phenylimidazole-2-methanol was boiled under reflux in a mixture of 85 ml. of glacial acetic acid, 8.5 ml. of water and 8.5 ml. of concentrated hydrochloric acid solution. Acetic acid was removed by evaporation and the base was liberated by addition of 2 N sodium hydroxide solution. It was crystallised from isopropyl alcohol. Melting point of the product was 162°-165° C.
後処理
- temperatureunder reflux in a mixture of 85 ml
- customAcetic acid was removed by evaporation
- additionthe base was liberated by addition of 2 N sodium hydroxide solution
- customIt was crystallised from isopropyl alcohol
- customwas 162°-165° C.
出典と根拠
- ORDレコード
- ord-cceeaee25d9846e69e81e02792f0e7c9
- 出典データセット
- uspto-grants-1979_05
- 特許番号
- US04152441
関連ノート
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