Sodium Hydroxide → 4-Amino-1,2,2,6,6-pentamethylpiperidine
反応式
C([NH:9][CH:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[N:13]([CH3:18])[C:12]([CH3:20])([CH3:19])[CH2:11]1)(=O)C1C=CC=CC=1.[OH-].[Na+]>Cl>[CH3:18][N:13]1[C:14]([CH3:16])([CH3:17])[CH2:15][CH:10]([NH2:9])[CH2:11][C:12]1([CH3:20])[CH3:19]参加物
4
実験手順
750 parts of 4-benzoylamino-1,2,2,6,6-pentamethyl piperidine are dissolved in 1000 parts of concentrated hydrochloric acid and the resulting solution is boiled under reflux for 10 hours. After cooling, sodium hydroxide is added until an alkaline reaction is obtained and the mixture is repeatedly extracted with methylene chloride. The residue obtained after removal of the methylene chloride by evaporation is distilled in vacuo, 300 parts of 1,2,2,6,6-pentamethyl-4-aminopiperidine boiling at 98° C./15 Torr distilling over.
後処理
- temperatureunder reflux for 10 hours
- temperatureAfter cooling
- customis obtained
- extractionthe mixture is repeatedly extracted with methylene chloride
- customThe residue obtained
- customafter removal of the methylene chloride
- customby evaporation
- distillationis distilled in vacuo, 300 parts of 1,2,2,6,6-pentamethyl-4-aminopiperidine boiling at 98° C./15 Torr
- distillationdistilling over
出典と根拠
- ORDレコード
- ord-af6339c97ec140c2aa1ff9798e8ac2ac
- 出典データセット
- uspto-grants-1979_05
- 特許番号
- US04153596
反応ノート
読み込み中…