Sodium Hydroxide → 4-Amino-1,2,2,6,6-pentamethylpiperidine

HRID 262043

反応式

HRID 262043 の反応式
C([NH:9][CH:10]1[CH2:15][C:14]([CH3:17])([CH3:16])[N:13]([CH3:18])[C:12]([CH3:20])([CH3:19])[CH2:11]1)(=O)C1C=CC=CC=1.[OH-].[Na+]>Cl>[CH3:18][N:13]1[C:14]([CH3:16])([CH3:17])[CH2:15][CH:10]([NH2:9])[CH2:11][C:12]1([CH3:20])[CH3:19]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 20382789N-(1,2,2,6,6-Pentamethylpiperidin-4-yl)benzamide

生成物 1

HCID 6937924-Amino-1,2,2,6,6-pentamethylpiperidine

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

750 parts of 4-benzoylamino-1,2,2,6,6-pentamethyl piperidine are dissolved in 1000 parts of concentrated hydrochloric acid and the resulting solution is boiled under reflux for 10 hours. After cooling, sodium hydroxide is added until an alkaline reaction is obtained and the mixture is repeatedly extracted with methylene chloride. The residue obtained after removal of the methylene chloride by evaporation is distilled in vacuo, 300 parts of 1,2,2,6,6-pentamethyl-4-aminopiperidine boiling at 98° C./15 Torr distilling over.

後処理

  1. temperatureunder reflux for 10 hours
  2. temperatureAfter cooling
  3. customis obtained
  4. extractionthe mixture is repeatedly extracted with methylene chloride
  5. customThe residue obtained
  6. customafter removal of the methylene chloride
  7. customby evaporation
  8. distillationis distilled in vacuo, 300 parts of 1,2,2,6,6-pentamethyl-4-aminopiperidine boiling at 98° C./15 Torr
  9. distillationdistilling over

出典と根拠

ORDレコード
ord-af6339c97ec140c2aa1ff9798e8ac2ac
出典データセット
uspto-grants-1979_05
特許番号
US04153596

関連ノート

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