N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine benzyl ester → N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine

HRID 262273

反応式

HRID 262273 の反応式
C([O:8][C:9](=[O:22])[C@H:10]([CH3:21])[NH:11][C:12](=[O:20])[CH:13]([CH3:19])[CH2:14][C:15]([O:17][CH3:18])=[O:16])C1C=CC=CC=1>C(O)C.[Pd]>[CH3:18][O:17][C:15]([CH2:14][CH:13]([CH3:19])[C:12]([NH:11][C@H:10]([C:9]([OH:22])=[O:8])[CH3:21])=[O:20])=[O:16]

参加物

4

反応物 1

HCID 53826083N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine benzyl ester

生成物 1

HCID 53969800N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine benzyl ester (50 g.) is dissolved in 95% ethanol, 10% palladium on charcoal (5 g.) is added and the mixture is hydrogenated at normal pressure for 16 hours. The catalyst is filtered off and the filtrate is concentrated to dryness in vacuo to yield N-(3-methoxycarbonyl-2-methylpropanoyl)-L-alanine.

後処理

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated to dryness in vacuo

出典と根拠

ORDレコード
ord-1ef4074e094e4767be54b6061fe62c15
出典データセット
uspto-grants-1979_05
特許番号
US04153725

関連ノート

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