反応式
Cl[C:2]1[C:3](C)=[N+:4]([O-])[CH:5]=[CH:6][CH:7]=1.[N+:10]([O-])([OH:12])=[O:11]>>[N+:10]([C:7]1[CH:6]=[CH:5][N:4]=[CH:3][CH:2]=1)([O-:12])=[O:11]参加物
3
実験手順
3-Chloro-2-methylpyridine N-oxide may be nitrated with a mixture of nitric acid and sulphuric acids, and the 4-nitropyridine produced successively treated with sodium methoxide, heated in acetic anhydride, purified and deacetylated to give 2-hydroxymethyl-3-chloro-4-methoxypyridine, which may be substituted for 2-hydroxy-3-methoxypyridine in the procedure of Example 1(ii)-(v) to prepare N-cyano-N'-methyl-N"-[2-((3-chloro-4-methoxy-2-pyridyl)methylthio)ethyl]guanidine.
出典と根拠
- ORDレコード
- ord-b3e0b71cc11a4bd8b593fa0e37e24879
- 出典データセット
- uspto-grants-1979_05
- 特許番号
- US04154838
関連ノート
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