Acetic Acid → 4-Chloro-1-naphthol

HRID 262537

反応式

HRID 262537 の反応式
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12]C)=[CH:4][CH:3]=1.C(O)(=O)C.Br>O>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([OH:12])=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6060381-Chloro-4-methoxynaphthalene

生成物 1

HCID 117874-Chloro-1-naphthol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The known compound 1-chloro-4-methoxynaphthalene is dissolved in 150 ml. of acetic acid and 150 ml. of 48 percent hydrobromic acid, and the mixture is heated at its reflux temperature for two hours. The mixture is diluted with 200 ml. of water and cooled to provide 1-chloro-4-hydroxynaphthalene as a crystalline solid.

後処理

  1. temperaturereflux temperature for two hours
  2. additionThe mixture is diluted with 200 ml

出典と根拠

ORDレコード
ord-4d56f003d2c74f3aaaf1273fc672b7bd
出典データセット
uspto-grants-1979_05
特許番号
US04154848

関連ノート

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