Thionyl Chloride → 2-Bromo-3,3,3-trifluoropropanoyl chloride
反応式
[Br:1][CH:2]([C:6]([F:9])([F:8])[F:7])[C:3](O)=[O:4].S(Cl)([Cl:12])=O>>[Br:1][CH:2]([C:6]([F:9])([F:8])[F:7])[C:3]([Cl:12])=[O:4]参加物
3
実験手順
A solution of 2-bromo-3,3,3-trifluoropropanoic acid (5 g.) in thionyl chloride (5 ml.) is refluxed in the steam bath for two hours. The excess thionyl chloride is removed in vacuo, and the residue distilled under reduced pressure to yield 2-bromo-3,3,3-trifluoropropanoic acid chloride.
後処理
- customThe excess thionyl chloride is removed in vacuo
- distillationthe residue distilled under reduced pressure
出典と根拠
- ORDレコード
- ord-10ae524558134f8d8f3774ea569f41d4
- 出典データセット
- uspto-grants-1979_05
- 特許番号
- US04154935
反応ノート
読み込み中…