Benzoyl chloride, 3-nitro- → 2'-Cyano-3,4'-dinitrobenzanilide

HRID 263053

反応式

HRID 263053 の反応式
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].[N+:13]([C:16]1[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=1)[C:19](Cl)=[O:20])([O-:15])=[O:14]>N1C=CC=CC=1>[C:4]([C:3]1[CH:6]=[C:7]([N+:10]([O-:12])=[O:11])[CH:8]=[CH:9][C:2]=1[NH:1][C:19](=[O:20])[C:18]1[CH:22]=[CH:23][CH:24]=[C:16]([N+:13]([O-:15])=[O:14])[CH:17]=1)#[N:5]

参加物

4

反応物 2

HCID 8495Benzoyl chloride, 3-nitro-HCID 285322-Amino-5-nitrobenzonitrile

生成物 1

HCID 213150352'-Cyano-3,4'-dinitrobenzanilide

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A solution of 8.16 gm. (0.05 mole) of 2-amino-5-nitrobenzonitrile and 9.28 gm. (0.05 mole) of m-nitro benzoyl chloride in 50 ml. of dry pyridine is refluxed for three hours. The pyridine is removed by distillation in vacuo and the solid residue triturated with water. There is obtained 15.3 gm. (95%) of a yellow solid that melts at 203°-205°. Recrystallization from aqueous ethanol (2:1) gives material melting at 205°-206°.

後処理

  1. customThe pyridine is removed by distillation in vacuo
  2. customthe solid residue triturated with water
  3. customThere is obtained 15.3 gm
  4. customRecrystallization from aqueous ethanol (2:1)

出典と根拠

ORDレコード
ord-02827a8b5306486fb644ed90a7cf4913
出典データセット
uspto-grants-1979_05
特許番号
US04156012

関連ノート

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