O-Cresol → 1,3-Dimethyl-5-(phenylaminocarbonyl methylene)-hydantoin

HRID 263096

反応式

HRID 263096 の反応式
[C:1]1([N:7]2[C:11](=[O:12])[CH:10]=[CH:9][C:8]2=[O:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:14][NH:15][C:16]([NH:18][CH3:19])=[O:17].C1(C)C(O)=CC=CC=1>>[CH3:14][N:15]1[C:9](=[CH:10][C:11]([NH:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[O:12])[C:8](=[O:13])[N:18]([CH3:19])[C:16]1=[O:17]

参加物

4

反応物 3

HCID 335O-CresolHCID 7293N,N'-DimethylureaHCID 13662N-Phenylmaleimide

生成物 1

HCID 540892721,3-Dimethyl-5-(phenylaminocarbonyl methylene)-hydantoin

実験手順

A solution of 17.3 parts of N-phenyl maleic imide and 8.8 parts of N,N'-dimethyl urea in 100 parts of cresol is stirred for three hours at 190° C. The solvent is distilled off in vacuo and the residue fractionated. The oily liquid which distills at a boiling point of 220° C./0.1 Torr solidifies after a while and may be recrystallised from n-propanol (Mp. 114°-115° C.). IR and NMR-spectra confirm the assumed compound.

後処理

  1. distillationThe solvent is distilled off in vacuo
  2. distillationThe oily liquid which distills at a boiling point of 220° C./0.1 Torr
  3. custommay be recrystallised from n-propanol (Mp. 114°-115° C.)

出典と根拠

ORDレコード
ord-8b024fb737aa439eb142cfe6c438d4a7
出典データセット
uspto-grants-1979_05
特許番号
US04156074

関連ノート

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