Sodium Hydroxide → 4-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one

HRID 263209ノート

反応式

HRID 263209 の反応式
Cl.[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH2:12])[CH2:5][CH2:4]1.[OH-].[Na+]>O>[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH2:12])[CH2:5][CH2:4]1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 233477954,5,6,7-Tetrahydro-7-oxobenzo[b]thiophen-4-amine hydrochloride

生成物 1

HCID 233477964-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The free amine is obtained by neutralizing the amine hydrochloride in water with sodium hydroxide solution. It is separated by extraction with CHCl3 and removal of the CHCl3 in vacuo affords 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophen-4-amine.

後処理

  1. customIt is separated by extraction with CHCl3 and removal of the CHCl3 in vacuo

出典と根拠

ORDレコード
ord-2bad3d0d21a04566a5356ca6bffb50e8
出典データセット
uspto-grants-1979_05
特許番号
US04156670

反応ノート

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