2,5-Dimethyl-1H-indole → 3-(4-Chloro-3-sulfamoylbenzoyl)-2,5-dimethylindole

HRID 263295

反応式

HRID 263295 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12].[CH3:15][C:16]1[NH:17][C:18]2[C:23]([CH:24]=1)=[CH:22][C:21]([CH3:25])=[CH:20][CH:19]=2.[Cl-].[Al+3].[Cl-].[Cl-]>ClC(Cl)C>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([C:24]2[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([CH3:25])[CH:22]=3)[NH:17][C:16]=2[CH3:15])=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12]

参加物

5

反応物 3

HCID 709652,5-Dimethyl-1H-indoleHCID 30179793-(Aminosulfonyl)-4-chlorobenzoyl chlorideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 213166093-(4-Chloro-3-sulfamoylbenzoyl)-2,5-dimethylindole

試薬・触媒・溶媒 1

HCID 63651,1-Dichloroethane溶媒

実験手順

is obtained as described in Example 10 (a) from 10 g 4-chloro-3-sulfamoylbenzoyl chloride and 7.8 g 2,5-dimethylindole in dichloro-ethane in the presence of 12 g aluminum chloride. M.p. 248°-250° C.

後処理

  1. customis obtained

出典と根拠

ORDレコード
ord-3d6c2c9aa8a744cf8b6d9ed661a2a213
出典データセット
uspto-grants-1979_05
特許番号
US04156732

関連ノート

読み込み中…