3-Methylbenzo[b]thiophene → 2-(4-Chloro-3-sulfamoylbenzoyl)-3-methyl-benzo[b]thiophene

HRID 263298

反応式

HRID 263298 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12].[CH3:15][C:16]1[C:17]2[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=2[S:19][CH:20]=1.[Cl-].[Al+3].[Cl-].[Cl-]>ClC1C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([C:20]2[S:19][C:18]3[CH:21]=[CH:22][CH:23]=[CH:24][C:17]=3[C:16]=2[CH3:15])=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12]

参加物

5

反応物 3

HCID 738173-Methylbenzo[b]thiopheneHCID 30179793-(Aminosulfonyl)-4-chlorobenzoyl chlorideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 213166392-(4-Chloro-3-sulfamoylbenzoyl)-3-methyl-benzo[b]thiophene

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

is obtained as described in Example 1 from 2.5 g 4-chloro-3-sulfamoylbenzoyl chloride, 1.6 g 3-methylbenzo[b]thiophene and 3 g aluminum chloride in 50 ml chlorobenzene. Colorless crystals, m.p. 210° C.

後処理

  1. customis obtained

出典と根拠

ORDレコード
ord-c924855fb6344a32ab7dcacaf651a47f
出典データセット
uspto-grants-1979_05
特許番号
US04156732

関連ノート

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