Sodium Hydroxide → HCID 178526703、化合物

HRID 26343

反応式

HRID 26343 の反応式
N[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[OH-:11].[Na+]>>[OH:11][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 778882-Amino-5-nitropyridine

生成物 1

HCID 178526703HCID 178526703、化合物収率 60%

反応条件

温度
102 °C

実験手順

A mixture containing 500 g (3.6 mol) of 2-amino-5-nitropyridine in 2000 ml of 10% sodium hydroxide was refluxed at about 102° C. for 10 hours, cooled and filtered. The filter cake was dissolved in water and neutralized with hydrochloric acid. The product was filtered and dried to give 301.7 g (60%) of product as a white powdery solid, m.p. 188°-190° C.

後処理

  1. temperaturecooled
  2. filtrationfiltered
  3. dissolutionThe filter cake was dissolved in water and neutralized with hydrochloric acid
  4. filtrationThe product was filtered
  5. customdried

出典と根拠

ORDレコード
ord-6ae7801ecbfb4c0cae743ecb62ed22a2
出典データセット
uspto-grants-1979_04
特許番号
US04149872

関連ノート

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