Succinic anhydride → Digeranyl Succinate

HRID 266665

反応式

HRID 266665 の反応式
[CH3:1][C:2](=[CH:4][CH2:5][CH2:6]/[C:7](=[CH:9]/[CH2:10][OH:11])/[CH3:8])[CH3:3].[OH:12][CH2:13]/[CH:14]=[C:15](/[CH3:22])\[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20].[C:23]1(=O)[O:28][C:26](=[O:27])[CH2:25][CH2:24]1>O>[C:23]([O:12][CH2:13]/[CH:14]=[C:15](/[CH2:16][CH2:17][CH:18]=[C:19]([CH3:21])[CH3:20])\[CH3:22])(=[O:28])[CH2:24][CH2:25][C:26]([O:11][CH2:10]/[CH:9]=[C:7](/[CH2:6][CH2:5][CH:4]=[C:2]([CH3:1])[CH3:3])\[CH3:8])=[O:27]

参加物

5

反応物 3

HCID 7922Succinic anhydrideHCID 637566GeraniolHCID 643820Nerol

生成物 1

HCID 22593555Digeranyl Succinate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Synthesis (c): A mixture of geraniol and nerol (approximately 70:30 by weight) in the amount of 94.86 g (0.615 mol) and succinic anhydride in the amount of 20.51 g (0.205 mol) are combined at room temperature. The mixture is heated to 140° C. for 6 h while water is removed using an argon sparge. After cooling to room temperature, the mixture is placed in a Kugelrohr oven and concentrated at 80°-85° C. for 5.5 h. Purity of the product is determined by thin layer chromatography and the structure confirmed by 13C and 1H NMR.

後処理

  1. customare combined at room temperature
  2. customis removed
  3. customsparge
  4. concentrationconcentrated at 80°-85° C. for 5.5 h

出典と根拠

ORDレコード
ord-5995f2c1161e45688b92fedd26e95de3
出典データセット
uspto-grants-1997_07
特許番号
US05652205

関連ノート

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