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Ethyl bromoacetate → HCID 178472639、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl bromoacetate | HCID 7748 | — |
| 反応物 | 1H-Benzimidazole, 1-methyl- | HCID 95890 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | HCID 178472639 | HCID 178472639 | 62% |
反応手順
The 1-methyl-benzimidazole of Step A was dissolved in ether and 1.4 equivalents of ethyl bromoacetate were added thereto. The ether solution was allowed to stand for several days and the crystals formed were recovered for a 62% yield of 1-ethoxycarbonylmethyl-3-methyl-benzimidazolium bromide. After crystallization from an ethyl acetate-methanol mixture, the product melted at 160°-161° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151280 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-1304c5c6f0684e9e96e83281b74b04e6 |
| 出典メモ | uspto-grants-1979_04 |