4-Hydroxybenzoic Acid → Benzoic acid, 4-(acetyloxy)-

HRID 26719

反応式

HRID 26719 の反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[C:11](Cl)(=[O:13])[CH3:12]>C1C=CC=CC=1>[C:11]([O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)(=[O:13])[CH3:12]

参加物

4

反応物 2

HCID 1354-Hydroxybenzoic AcidHCID 6367Acetyl chloride

生成物 1

HCID 16865Benzoic acid, 4-(acetyloxy)-

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A solution of 20 g. of 4-hydroxybenzoic acid in 200 ml. of benzene and 40 ml. of acetyl chloride is refluxed for 3 hours. Solvent and excess acetyl chloride are evaporated. The mixture is dissolved in methanol (150 ml.) and water (20 ml.) added; after 15 minutes, addition of more water results in the precipitation of 4-acetoxy benzoic acid, m.p. 192°-193° C.

後処理

  1. customSolvent and excess acetyl chloride are evaporated
  2. dissolutionThe mixture is dissolved in methanol (150 ml.)
  3. additionwater (20 ml.) added
  4. additionaddition of more water

出典と根拠

ORDレコード
ord-97e6103d3157480888b34d018a955edc
出典データセット
uspto-grants-1979_04
特許番号
US04151297

関連ノート

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