Potassium Hydroxide → chrysanthemic acid d-trans-form

HRID 267574

反応式

HRID 267574 の反応式
[CH3:1][C:2]([CH3:13])=[CH:3][CH:4]1[C:6]([CH3:8])([CH3:7])[CH:5]1[C:9]([O:11][CH3:12])=[O:10].[OH-].[K+]>CO>[CH3:1][C:2]([CH3:13])=[CH:3][C@H:4]1[C:6]([CH3:7])([CH3:8])[C@@H:5]1[C:9]([OH:11])=[O:10].[CH3:1][C:2]([CH3:13])=[CH:3][CH:4]1[C:6]([CH3:7])([CH3:8])[CH:5]1[C:9]([O:11][CH3:12])=[O:10]

参加物

5

反応物 2

HCID 14797Potassium HydroxideHCID 91127Methyl chrysanthemate

生成物 2

HCID 16747chrysanthemic acid d-trans-form収率 83%HCID 91127Methyl chrysanthemate

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

In a 100 ml volume four-necked flask, there were charged methyl chrysanthemate consisting of 40.0 % of the cis-isomer and 60.0 % of the trans-isomer (20.0 g; trans-isomer, 0.066 mol), a 10 % aqueous solution of potassium hydroxide (33 g; 0.059 mol) and methanol (20 g), and the mixture was stirred at 50°C for 4 hours as in Example 1. After the removal of methanol by distillation, the reaction mixture was treated as in Example 4 to give trans-chrysanthemic acid (9.4 g; trans-isomer, 83 %) and unreacted methyl chrysanthemate (9.6 g).

後処理

  1. customAfter the removal of methanol
  2. distillationby distillation
  3. additionthe reaction mixture was treated as in Example 4

出典と根拠

ORDレコード
ord-78257b6ef7db47e78132e2a733b3fcf6
出典データセット
uspto-grants-1976_03
特許番号
US03943167

関連ノート

読み込み中…