Dibenzoylmethane → Tribenzoylmethane

HRID 268507

反応式

HRID 268507 の反応式
[C:1]([O:7]CC)(=O)[CH2:2][C:3]([CH3:5])=[O:4].[C:10]([CH:15]1[CH2:19][CH2:18][CH2:17][C:16]1=[O:20])(OCC)=O.C[CH:22]([C:26](=O)[CH3:27])[C:23](=O)[CH3:24].[C:29](F)(=O)C.[C:33]([CH:36]([C:42]([CH3:44])=O)C(OCC)=O)(=O)[CH3:34].[C:45]([C:48]1([C:54](OCC)=O)[CH2:52][CH2:51][CH2:50][C:49]1=O)(=[O:47])[CH3:46].C(C(C)(C(=O)C)C(=O)C)(=O)C.C(CC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.C(F)(=O)C1C=CC=CC=1>>[C:16]([CH:2]([C:1](=[O:7])[C:49]1[CH:50]=[CH:51][CH:52]=[CH:48][CH:54]=1)[C:3](=[O:4])[C:5]1[CH:27]=[CH:26][CH:22]=[CH:23][CH:24]=1)(=[O:20])[C:15]1[CH:10]=[CH:29][CH:17]=[CH:18][CH:19]=1.[C:45]([CH:2]([C:1](=[O:7])[C:10]1[CH:15]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:3](=[O:4])[C:5]1[CH:44]=[CH:42][CH:36]=[CH:33][CH:34]=1)(=[O:47])[CH3:46]

参加物

11

反応物 9

HCID 8433Dibenzoylmethane2 回HCID 8868Ethyl AcetoacetateHCID 11204Acetyl fluoride2 回HCID 67999Benzoyl fluorideHCID 69136Ethyl 2-oxocyclopentanecarboxylateHCID 699493-Methyl-2,4-pentanedioneHCID 79063Ethyl 2-acetylacetoacetateHCID 121311812,4-Pentanedione, 3-acetyl-3-methyl-HCID 214389482-Acetyl-2-carbethoxycyclopentanone

生成物 2

HCID 413869TribenzoylmethaneHCID 7863132-Benzoyl-1-phenyl-1,3-butanedione

実験手順

When the thallous salts of ethyl acetoacetate, 2-carbethoxycyclopentanone, and 3-methylpentane-2,4-dione, prepared according to Example 1, are treated with acetyl fluoride at room temperature as described in Example 4, ethyl 2-acetyl-acetoacetate, 2-acetyl-2-carbethoxycyclopentanone, and 3-acetyl-3-methylpentane-2,4-dione, respectively, are obtained in 95% yield. Tribenzoylmethane is prepared by treating the thallous salt of dibenzoylmethane with benzoyl fluoride in the same manner. Acetyldibenzoylmethane is prepared by treating the thallous salt of dibenzoylmethane with acetyl fluoride.

後処理

  1. customrespectively, are obtained in 95% yield

出典と根拠

ORDレコード
ord-9f27d11f015549b89859d82d99f296af
出典データセット
uspto-grants-1976_03
特許番号
US03947488

関連ノート

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