Ethanol → (1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

HRID 268598ノート

反応式

HRID 268598 の反応式
[CH2:1]([N:3]1[C:7]([CH:8]=[N:9][OH:10])=[N:6][CH:5]=[N:4]1)[CH3:2].[CH2:11]([OH:13])[CH3:12]>[OH-].[OH-].[Pd+2]>[C:11]([O-:10])(=[O:13])[CH3:12].[CH2:1]([N:3]1[C:7]([CH2:8][NH3+:9])=[N:6][CH:5]=[N:4]1)[CH3:2]

参加物

4

反応物 2

HCID 702EthanolHCID 136335088HCID 136335088、化合物

生成物 1

HCID 86603337(1-Ethyl-1H-1,2,4-triazol-5-yl)methylammonium acetate

試薬・触媒・溶媒 1

HCID 9942167Palladium hydroxide触媒

実験手順

A mixture of 1-ethyl-1H-1,2,4-triazole-5-carbaldehyde oxime (6.17 g, 44 mmol), 10% palladium hydroxide on carbon (2.9 g) acetic acid (125 mL) and ethanol (125 mL) were stirred under an atmosphere of hydrogen for 14 hours. The reaction mixture was filtered and concentrated in vacuo to give the title compound (7.7 g) 1H-NMR (d6-DMSO) δ 1.32 (3H, t, J=7 Hz), 1.89 (3H, s), 3.89 (2H, br), 4.17 (2H, q, J=7 Hz), 7.80 (1H, s).

後処理

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-bab6cf9741d448c0be083d102f1aedc7
出典データセット
uspto-grants-2008_11
特許番号
US07446117B2

反応ノート

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