3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid

HRID 26922

反応式

[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH3:20])=[CH:16][C:17]([OH:19])=[O:18])=[CH:11][CH:10]=1>O=[Pt]=O.O1CCOCC1>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][C:12]([CH:15]([CH3:20])[CH2:16][C:17]([OH:19])=[O:18])=[CH:11][CH:10]=1

参加物

実験手順

1 g. of 3-(2',4'-difluoro-4-biphenylyl)-2-butenoic acid is dissolved in 25 ml. of dioxane. 0.1 g. of PtO2 is added and the hydrogenation is carried out at 20° under normal pressure until hydrogen absorption has ceased. The mixture is filtered and the filtrate is evaporated to give 3-(2',4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.

後処理

customthe hydrogenation is carried out at 20° under normal pressure until hydrogen absorption
filtrationThe mixture is filtered
customthe filtrate is evaporated

出典と根拠

ORDレコード: ord-0147196874c445caa05e8ce4ff012648
出典データセット: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04151302

反応式

参加物

反応物 1

生成物 1

試薬・触媒・溶媒 2

実験手順

後処理

出典と根拠

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